E17 Intestinal homeostasis: A balancing act between effector and regulatory T cells
نویسندگان
چکیده
منابع مشابه
Balancing between immunity and tolerance: an interplay between dendritic cells, regulatory T cells, and effector T cells.
Dendritic cells (DC), professional antigen-presenting cells of the immune system, exert important functions both in induction of T cell immunity, as well as tolerance. It is well established that the main function of immature DC (iDC) in their in vivo steady-state condition is to maintain peripheral tolerance to self-antigens and that these iDC mature upon encounter of so-called danger signals ...
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Immune responses to infection are optimally designed to generate large numbers of effector T cells while simultaneously minimizing the collateral damage of their potentially lethal actions and generating memory T cells to protect against subsequent encounter with pathogens. Much remains to be discovered about how these equally essential processes are balanced to enhance health and longevity and...
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CD4(+) T cell compartments in mouse and man are composed of multiple distinct subsets each possessing unique phenotypic and functional characteristics. IL-17-producing CD4(+) T cells (Th17 cells) represent a distinct subset of the CD4(+) T cell lineage. Recent evidence suggests that Th17 cells carry out effector functions similar to cytotoxic CD8(+) T cells and play an important role in the cle...
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PURPOSE OF REVIEW The tight control of blood magnesium (Mg) levels is of central importance for numerous physiological processes. A persistent low Mg status (hypomagnesemia) is associated with severe health risks and is involved in the pathogenesis of type 2 diabetes mellitus, osteoporosis, asthma, and heart and vascular diseases. The current view has expanded significantly as a result of the i...
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ژورنال
عنوان ژورنال: Journal of Crohn's and Colitis Supplements
سال: 2010
ISSN: 1873-9954
DOI: 10.1016/s1873-9954(10)70021-5